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Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy

Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy

May 20, 2025 Category: Blog

Chimeric antigen receptor (CAR) T cell efficacy against solid tumors is currently limited by several immune escape mechanisms, which may include tumor-derived extracellular vesicles.Advanced neuroblastoma is an aggressive childhood tumor without curative treatment Controllers options for most relapsed patients today.We here evaluated the role of tu

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Reference genes for quantitative gene expression studies in multiple avian species.

May 20, 2025 Category: Blog

Quantitative real-time PCR (qPCR) rapidly and reliably quantifies gene expression levels across different experimental conditions.Selection of suitable reference genes is essential for meaningful normalization and thus correct interpretation of data.In recent years, an increasing number of avian species other than the chicken Lunge Pads has been in

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Admittance Matrix Validation for Power Distribution System Models Using a Networked Equipment Model Framework

May 20, 2025 Category: Blog

The evolving nature of electric power distribution systems is motivating the development of advanced applications for utility planning, operation, management, and control.These model-based applications interact with multiple subsystems within software platforms referred to as advanced distribution management systems.Recently, the Common Information

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Ethnobotanical study of medicinal plants in Ganta Afeshum District, Eastern Zone of Tigray, Northern Ethiopia

May 20, 2025 Category: Blog

Abstract Background Starting from the ancient time, the people of Ethiopia use medicinal plants as traditional medicine to heal different human and livestock ailments.This ethnobotanical study of medicinal plants was carried out in Ganta Afeshum District, Eastern Zone of Tigray, Northern Ethiopia, to identify medicinal plant species used by the loc

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